Longevity Legacy is a Marietta, Georgia functional and holistic medicine practice led by Dr. Gena Mastrogianakis, M.D., IFMCP — a board-certified Family Physician with advanced training in Functional Medicine, Holistic Medicine, Longevity Medicine, Prolozone Therapy, Peptide Therapy, Anti-Aging Medicine, Bio-Identical Hormone Replacement, and Restorative Systems. Rather than chasing symptoms, Dr. Mastrogianakis focuses on identifying root causes and designing individualized treatment plans that address the underlying drivers of chronic illness. The practice serves patients of all ages with a whole-person philosophy that takes into account body systems, lifestyle, emotional health, stress, and relaxation — with appointments that last as long as each patient needs and care delivered both in person and via telehealth.

About the Physician

Dr. Mastrogianakis is a Board-Certified Family Medicine Physician and Certified Practitioner of the Institute for Functional Medicine (IFMCP) — a credential held by a small percentage of physicians worldwide. She founded Longevity Legacy to offer patients what she found missing in conventional medicine: genuine hope and a real solution for chronic illness. Her clinical toolkit extends well beyond what most physicians offer, incorporating advanced training in longevity medicine, peptide therapy, prolozone (ozone) therapy for joint health, bioidentical hormone replacement, detoxification, and restorative systems. Her approach prioritizes natural therapies — whole food nutrition, herbs, movement, emotional balance, and targeted supplementation — calibrated against comprehensive laboratory data to deliver precision care for each individual. She started this practice to give her patients the same gift she had received: a healthier life and renewed hope.

Services Offered

• Personalized Nutritional Plan — Individualized dietary guidance built around each patient's lab results, health history, and goals — emphasizing whole foods, anti-inflammatory eating, and metabolic support for sustainable, long-term health improvement.
• Supplementation Based on Lab Results — Evidence-guided supplementation protocols derived directly from comprehensive laboratory testing — ensuring patients receive targeted nutrients based on their actual deficiencies, not generic recommendations.
• Detoxification & Inflammation Therapies — Structured detoxification protocols and anti-inflammatory interventions designed to reduce toxic burden, lower systemic inflammation, and restore normal cellular function across organ systems.
• Fasting & Fasting-Mimicking Protocols — Physician-supervised fasting and fasting-mimicking diet programs harnessing the metabolic and cellular renewal benefits of caloric restriction to support weight management, metabolic health, and longevity.
• Prolozone Therapy (Ozone for Joint Health) — Ozone injected directly into arthritic or painful joints stimulates healing, reduces inflammation, and can eliminate or significantly reduce joint pain — a powerful regenerative alternative to cortisone or surgery.
• Bio-Identical Hormone Replacement (BHRT) — Individualized BHRT programs addressing thyroid, adrenal, and sex hormone imbalances in women and men — restoring hormonal equilibrium to improve energy, mood, weight, libido, and overall quality of life.
• Hormone Balancing Program — A comprehensive program targeting hormone dysregulation through advanced testing, lifestyle interventions, nutritional support, and personalized prescribing — coordinating all hormonal systems for optimal function.
• Rejuvenating Peptide Therapies — Targeted peptide protocols (including BPC-157, sermorelin, and others) to support tissue repair, cellular regeneration, lean muscle maintenance, cognitive function, and anti-aging at the molecular level.

What to Expect

Longevity Legacy is located at 3417 Canton Road, Building 2, Marietta, GA 30066. Call (404) 807-0300 to schedule. The practice operates by appointment only and does not accept insurance — major credit cards, HSA, and FSA are accepted. Both in-person and telehealth appointments are available. Learn more at mylongevitylegacy.com.